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| March/April 2008 |
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| CARDIOVASCULAR |
| The following papers have been extracted and commented upon: |
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| Diaz R, Goyal A, Mehta SR et al. Glucose-insulin-potassium therapy in patients with ST-segment elevation myocardial infarction. JAMA 2007; 298: 23992405. |
| Evidence Level: II |
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| McMurray JJV, Teerlink JR, Cotter G et al. Effects of tezosentan on symptoms and clinical outcomes in patients with acute heart failure: the VERITAS randomized controlled trials. JAMA 2007; 298: 20092019. |
| Evidence Level: II |
| ICM RECOMMENDED REVIEW PAPER |
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| Tapson VF. Acute pulmonary embolism. N Engl J Med 2008;358:1037-1052. 98 references. |
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| END OF LIFE |
| ICM RECOMMENDED REVIEW PAPERS |
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| Qaseem A, Snow V, Shekelle P, Casey Jr DE, Cross JT, Owens DK for the Clinical Efficacy Assessment Subcommitttee of the American College of Physicians. Evidence-based interventions to improve the palliative care of pain, dyspnea, and depression at the end of life: A clinical practice guideline from the American College of Physicians. Ann Intern Med 2008;148:141-146. 54 references. |
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| Lorenz KA, Lynn J, Dy SM et al. Evidence for improving palliative care at the end of life: A systematic review. Ann Intern Med 2008;148:147-149. 152 references. |
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| Goldstein NE, Fischberg D. Update in palliative medicine. Ann Intern Med 2008;148:135-140. 23 references. |
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| GASTROINTESTINAL |
| The following paper has been extracted and commented upon: |
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| Hickson M, D'Souza AL, Muthu N et al. Use of probiotic Lactobacillus preparation to prevent diarrhoea associated with antibiotics: randomised double blind placebo controlled trial. BMJ 2007; 335: 80-85. |
 | 'Hot' topic | |
| Evidence Level: II |
| ICM RECOMMENDED REVIEW PAPER |
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| Frossard J-L, Steer ML, Pastor CM. Acute pancreatitis. Lancet 2008;371:143-152. 126 references. |
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| HEPATOLOGY |
| ICM RECOMMENDED REVIEW PAPER |
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| Stravitz RT, Kramer AH, Davern T et al. Intensive care of patients with acute liver failure: Recommendations of the U.S. Acute Liver Failure Study Group. Crit Care Med 2007;35:2498-2508. 136 references. |
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| METABOLISM |
| ICM RECOMMENDED REVIEW PAPER |
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| Kitabchi AE, Freire AX, Umpierrez GE. Evidence for strict inpatient blood glucose control: time to revise glycemic goals in hospitalized patients. Metabol Clin Experimental 2008;57:116-120. 44 references. |
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| NEUROLOGY |
| ICM RECOMMENDED REVIEW PAPERS |
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| Sendi P, Bregenzer T, Zimmerli W. Spinal epidural in clinical practice. Q J Med 2008;101:1-12. 88 references. |
| Logan SAE, MacMahon E. Viral meningitis. BMJ 2008; 336:36-40. 30 references. |
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| ORGANIZATION |
| ICM RECOMMENDED REVIEW PAPER |
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| Towey RM, Ojara S. Intensive care in the developing world. Anaesthesia 2007;62(Suppl. 1):32-37. 31 references. |
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| OUTCOME |
| The following paper has been extracted and commented upon: |
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| Garnacho-Montero J, Ortiz-Leyba C, Herrera-Melero I et al. Mortality and morbidity attributable to inadequate empirical antimicrobial therapy in patients admitted to the ICU with sepsis: a matched cohort study. J Antimicrob Chemother 2008; 61: 436441. |
| Evidence Level: III |
| ICM RECOMMENDED REVIEW PAPER |
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| Stroebe M, Schut H, Stroebe W. Health outcomes of bereavement. Lancet 2007;370:1960-1973. 187 references. |
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| PAEDIATRIC |
| The following paper has been extracted and commented upon: |
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| Duffett M, Choong K, Ng V, Randolph A, Cook DJ.Surfactant therapy for acute respiratory failure in children: a systematic review and meta-analysis. Crit Care 2007: 11: R66 (doi:10.1186/cc5944) |
 | Level 1 paper | |
| Evidence Level: I |
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| RENAL |
| The following papers have been extracted and commented upon: |
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| Kheterpal S, Tremper KK, Englesbe MJ et al. Predictors of postoperative acute renal failure after noncardiac surgery in patients with previously normal renal function. Anesthesiology 2007; 107: 892902. |
| Evidence Level: IV |
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| Kelly AM, Dwamena B, Cronin P, Bernstein SJ, Carlos RC. Meta-analysis: effectiveness of drugs for preventing contrast-induced nephropathy. Ann Intern Med 2008; 148: 284294. |
 | Level 1 paper | |
| Evidence Level: I |
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| RESPIRATORY |
| The following papers have been extracted and commented upon: |
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| Lorente L, Lecuona M, Jimnez A et al. Influence of an endotracheal tube with polyurethane cuff and subglottic secretion drainage on pneumonia. Am J Respir Crit Care Med 2007;176:1079-1083. |
| Evidence Level: II |
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| Meersseman W, Lagrou K, Maertens J et al. Galactomannan in broncho-alveolar lavage fluid. A tool for diagnosing aspergillosis in intensive care unit patients. Am J Respir Crit Care Med 2008;177:2734. |
 | Bright idea | |
| Evidence Level: III |
| ICM RECOMMENDED REVIEW PAPERS |
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| Mazzulli T. Value of RVP in clinical settings: intensive care. J Clin Virol 2007;40:S55-S57. 19 references. |
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| Writing Committee of the Second World Health Organization Consultation on Clinical Aspects of Human Infection with Avian Influenza A (H5N1) Virus. Update on avian influenza (H5N1) virus infection in humans. N Engl J Med 2008; 358:261-273. 76 references. |
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| Muscarella LF. Reassessment of the risk of healthcare-acquired infection during rigid laryngoscopy. J Hosp Infection 2008;68:101-107. 55 references. |
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| SEPSIS |
| The following papers have been extracted and commented upon: |
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| Dellinger RP, Levy MM, Carlet JM et al; for the International Surviving Sepsis Campaign Guidelines Committee. Surviving Sepsis Campaign: International guidelines for management of severe sepsis and septic shock: 2008 Crit Care Med 2008;36:296327. Also published in Intensive Care Med 2008;34:17-60. |
| Evidence Level: V |
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| Anthony KB, Fishman NO, Linkin DR, Gasink LB, Edelstein PH, Lautenbach E. Clinical and microbiological outcomes of serious infections with multidrug-resistant Gram-negative organisms treated with tigecycline. Clin Infect Dis 2008; 46: 567570. |
| Evidence Level: IV |
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| Kim S-H, Kim K-H, Kim H-B et al. Outcome of vancomycin treatment in patients with methicillin-susceptible Staphylococcus aureus bacteremia. Antimicrobial Agents Chemother 2008; 52: 192197. |
 | Could change clinical practice | |
| Evidence Level: III |
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| Trautmann M, Pollitt A, Loh U et al. Implementation of an intensified infection control program to reduce MRSA transmissions in a German tertiary care hospital. Am J Infect Control 2007; 35: 643-649. |
 | Could change clinical practice | |
| Evidence Level: IV |
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| Pashman J, Bradley EH, Wang H, Higa B, Fu M, Dembry LM. Promotion of hand hygiene techniques through use of a surveillance tool. J Hosp Infect 2007; 66: 249254. |
| Evidence Level: V |
| ICM RECOMMENDED REVIEW PAPERS |
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| Dancer SJ. The effect of antibiotics on methicillin-resistant Staphylococcus aureus. J Antimicrob Chemother 2008; 61:246-253. 88 references. |
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| Rice LB. The Maxwell Finland Lecture: For the duration rational antibiotic administration in an era of antimicrobial resistance and Clostridium difficile. Clin Infect Dis 2008; 46:491-496. 32 references. |
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| Sax H, Allegranzi B, Ukay I, Larson E, Boyce J, Pittet D. My five moments for hand hygiene: a user-centred design approach to understand, train, monitor and report hand hygiene. J Hosp Infection 2007;67:9-21. 72 references. |
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