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| May/June 2009 |
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| CARDIOVASCULAR |
| ICM RECOMMENDED REVIEW PAPER |
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| Chua D, Ignaszewski A. Clopidogrel in acute coronary syndromes. BMJ 2009;338:b1180.doi:10.1136/bmj.b1180. 25 references. |
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| ETHICS |
| The following papers have been extracted and commented upon: |
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| Evans LR, Boyd EA, Malvar G et al. Surrogate decision-makers' perspectives on discussing prognosis in the face of uncertainty. Am J Respir Crit Care Med 2009;179:48Ð53. |
| Evidence Level: III |
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| White DB, Katz MH, Luce JM, Lo B. Who should receive life support during a public health emergency? Using ethical principles to improve allocation decisions. Ann Intern Med 2009;150:132Ð138. |
| Evidence Level: IV |
| ICM RECOMMENDED REVIEW PAPER |
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| Seder DH. Death and hope in the ICU. Ann Intern Med 2008;149:764-765. No references. |
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| HAEMATOLOGY |
| ICM RECOMMENDED REVIEW PAPERS |
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| Mackman N. The role of tissue factor and factor VIIa in hemostasis. Anesth Analg 2009; 108:1447-1452. 51 references. |
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| Tanaka KA, Key NS. Levy JH. Blood coagulation: hemostasis and thrombin regulation. Anesth Analg 2009; 108:1433-1446. 153 references. |
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| METABOLIC |
| The following paper has been extracted and commented upon: |
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| The NICE-SUGAR Study Investigators. Intensive versus conventional glucose control in critically ill patients. N Engl J Med 2009;360:1283Ð1297. |
 | Could change clinical practice | |
| Evidence Level: II |
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| NEUROLOGY |
| The following papers have been extracted and commented upon: |
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| Angles EM, Robinson TN, Biffl WL et al. Risk factors for delirium after major trauma. Am J Surg 2008;196:864Ð870. |
| Evidence Level: IV |
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| Den Hertog HM, van der Worp HB, Tseng MC, Dippel DWJ. Cooling therapy for acute stroke. Cochrane Database of Systematic Reviews 2009, Issue 1. Art. No.: CD001247. DOI: 10.1002/14651858.CD001247.pub2. |
 | Level 1 paper | |
| Evidence Level: I |
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| ICM RECOMMENDED REVIEW PAPER |
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| Nichol AD, Cooper DJ. Can we improve neurological outcomes in severe traumatic brain injury? Injury 2009;doi:10/1016/j.injury.2009.01.002. 106 references. |
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| ORGANIZATION |
| The following papers have been extracted and commented upon: |
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| Kernisan LP, Lee SJ, Boscardin WJ, Landefield CS, Dudley RA. Association between hospital-reported Leapfrog Safe Practices Scores and inpatient mortality. JAMA 2009;301:1341Ð1348. |
| Evidence Level: IV |
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| Lott JP, Iwashyna TJ, Christie JD, Asch DA, Kramer AA, Kahn JM. Critical illness outcomes in specialty versus general intensive care units. Am J Respir Crit Care Med 2009;179:676Ð683. |
 | 'Hot' topic | |
| Evidence Level: IV |
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| Mador RL, Shaw NT. The impact of a Critical Care Information System (CCIS) on time spent charting and in direct patient care by staff in the ICU: a review of the literature. Int J Med Inform 2009; doi:10.1016/j.ijmedinf. |
 | 'Hot' topic | |
| Evidence Level: IV |
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| ICM RECOMMENDED REVIEW PAPER |
| Gajic O, Afessa B. Physician staffing models and patient safety in the ICU. Chest 2009 135:1038-1044.57 references. |
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| PAEDIATRIC |
| The following paper has been extracted and commented upon: |
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| Nishisaki A, Hales R, Biagas K et al. A multi-institutional high-fidelity simulation Òboot campÓ orientation and training program for first year pediatric critical care fellows. Pediatr Crit Care Med 2009;10:157Ð162. |
| Evidence Level: III |
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| RESPIRATORY |
| The following paper has been extracted and commented upon: |
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| Tessmer A, Welte T, Martus P, Schnoor M, Marre R, Suttorp N. Impact of intravenous b-lactam/macrolide versus b-lactam monotherapy of mortality in hospitalized patients with community-acquired pneumonia. J Antimicrob Chemother 2009;63:1025Ð1033. |
| Evidence Level: III |
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| Venditti M, Falcone M, Corrao S, Licata G, Serra P. Outcomes of patients hospitalized with community-acquired, health care- associated, and hospital-acquired pneumonia.Ann Intern Med 2009;150:19Ð26. |
| Evidence Level: IV |
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| SEPSIS |
| The following papers have been extracted and commented upon: |
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| Burton DC, Edwards JR, Horan TC, Jernigan JA, Fridkin SK. Methicillin-resistant Staphylococcus aureus central lineÐassociated bloodstream infections in US intensive care units, 1997-2007. JAMA 2009;301:727Ð736 |
 | 'Hot' topic | |
| Evidence Level: IV |
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| Timsit J-F, Schwebel C, Bouadma L et al. Chlorhexidine-impregnated sponges and less frequent dressing changes for prevention of catheter-related infections in critically ill adults. A randomized controlled trial. JAMA 2009; 301: 1231Ð1241. |
| Could change clinical practice |
| Evidence Level: II |
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| ICM RECOMMENDED REVIEW PAPERS |
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| Brady RRW, Verran J, Damani NN, Gibb AP. Review of mobile communication devices as potential reservoirs of nosocomial pathogens. J Hosp Infect 2009;71:295-300. 39 references. |
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| Brouqui P, Puro V, Fusco FM et al. for the EUNID Working Group. Infection control in the management of highly pathogenic infectious diseases: consensus of the European Network of Infectious Disease. Lancet Infect Dis 2009; 9:301-311. 110 references. |
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| Coffin SE, Klompas M, Classen D et al. Strategies to prevent ventilator-associated pneumonia in acute care hospitals. Infect Control Hosp Epidemiol 2008;29:S31-S40. 138 references. |
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| Craven DE, Chroneou A, Zias N, Hjalmarson K. Ventilator-associated tracheobronchitis (VAT): the impact of targeted antibiotic therapy on patient outcomes. Chest 2009; 135:521-528. 36 references. |
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| Lappin E, Ferguson AJ. Gram-positive toxic shock syndromes. Lancet Infect Dis 2009;9:281-290. 94 references. |
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| Lawrence KL, Kollef MH. Antimicrobial stewardship in the intensive care unit. Am J Respir Crit Care Med 2009; 179:434-438. 60 references. |
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| Roberts JA, Lipman J. Pharmacokinetic issues for antibiotics in the critically ill patient. Crit Care Med 2009;37:840-851. 165 references. |
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| TRAUMA |
| ICM RECOMMENDED REVIEW PAPER |
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| Enoch S, Roshan A, Shah M. Emergency and early management of burns and scalds. BMJ 2009;338: b1037doi:10.1136/bmj.b1037. 24 references. |
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